The exact cause of the disease is still not known and a small number of cases are inherited. While most cases are sporadic, with no clear genetic cause, a small percentage are linked to specific genetic mutations.
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One of the first early warning signs of ALS is muscle twitches. Other early signs include clumsiness, dropping things, and tripping or stumbling due to weakness in the arms and legs. ALS is generally fatal or terminal and can end in death.
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There is no cure for ALS and the average life expectancy after diagnosis is 2 to 4 years. However, some people live longer with the help of treatments and supportive care.
The diagnosis of ALS is based on the signs and symptoms of upper and lower motor neuron degeneration, as well as tests to rule out other conditions.
The treatment of ALS aims to slow down the disease progression, prevent complications, and improve the quality of life of people living with ALS.


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