Mary Mouser was diagnosed with type 1 diabetes at the age of 13. Mouser began her career at the age of six when she was chosen as a photo double for Abigail Breslin’s character in Signs.
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Mary Mouser was featured on the Starz Kids & Family series Eloise: The Animated Series as the voice of Eloise.

Mouser did voice work for animated features such as Dragon Hunters, Tarzan II, and Pom Poko. Mouser has appeared on a Mind Field episode (S2 E5) on the channel VSauce on YouTube.
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Mary Mouser was a voice actress in the audio drama series, Adventures in Odyssey as Samantha McKay, younger sister of Grady McKay.
Mary Mouser has appeared in guest starring roles on CSI: Crime Scene Investigation, Without a Trace, The King of Queens, Monk, Inconceivable, Scrubs, and One Life to Live.
At the 2006 Best of Fest Awards at the KIDS FIRST! Film and Video Festival, Mary Mouser received the Outstanding Performance Award for her voiceover work in Eloise: The Animated Series.


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