What is the main cause of amyloidosis? What are the 3 types of amyloidosis?

Amyloidosis is caused by the abnormal accumulation of amyloid proteins in tissues and organs.

Some of the risk factors for amyloidosis include Age since the risk of developing amyloidosis increases with age, Gender, with a higher risk in men; and Family history via genetic mutations.

There are three main types of amyloidosis, each of which is associated with different types of amyloid protein and underlying health conditions. These include AL amyloidosis (immunoglobulin light chain amyloidosis), AA amyloidosis (secondary amyloidosis) and ATTR amyloidosis (hereditary and wild-type).

There are also other rare types of amyloidosis, such as beta-2 microglobulin amyloidosis and dialysis-related amyloidosis. In amyloidosis, abnormal proteins are produced and deposited in tissues and organs, causing damage to their structure and function.

Organs that may be affected include the heart, kidneys, liver, spleen, nervous system and digestive tract. In amyloidosis, abnormal proteins are produced and deposited in tissues and organs, causing damage to their structure and function. Some types of amyloidosis occur with other diseases.