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Which cream is best for psoriasis?

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Psoriasis is a chronic inflammatory skin disorder that causes red, scaly, itchy, and flaky patches on the skin. There are many types of creams and ointments available for psoriasis, but they have different ingredients, benefits, side effects, and costs.

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Here are some of the most common ones and how they work:

Corticosteroids: These are anti-inflammatory drugs that reduce swelling, redness, and itching. They are available in different strengths, from mild to very potent. They are usually applied once or twice a day during flares, and less often during remission. Some examples are hydrocortisone, triamcinolone, and clobetasol. Corticosteroids can thin the skin, cause stretch marks, acne, or hair growth, and affect the adrenal glands if used for a long time or over large areas of the body.

Psoriasis/ Image Credits: HealthCentral

Vitamin D analogues: These are synthetic forms of vitamin D that slow down the growth of skin cells. They are usually applied once or twice a day. Some examples are calcipotriene and calcitriol. Vitamin D analogues can cause skin irritation, dryness, or peeling, and increase the risk of high calcium levels in the blood if used with calcium supplements or certain medications.

Retinoids: These are derivatives of vitamin A that normalize the growth and shedding of skin cells. They are usually applied once or twice a day. An example is tazarotene. Retinoids can cause skin irritation, burning, stinging, or sensitivity to light. They are not recommended for pregnant or breastfeeding women or those who plan to become pregnant.

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Calcineurin inhibitors: These are drugs that suppress the immune system and reduce inflammation. They are usually applied twice a day. Some examples are tacrolimus and pimecrolimus . Calcineurin inhibitors can cause skin irritation, burning, stinging, or infection. They may also increase the risk of skin cancer or lymphoma if used for a long time or over large areas of the body.

Coal tar: This is a byproduct of coal processing that reduces scaling, itching, and inflammation. It is available in different forms, such as ointments, creams, shampoos, or bath solutions. It is usually applied once or twice a day or as needed. Some examples are Psoriasin and MG217. Coal tar can cause skin irritation, staining of clothes or skin, or sensitivity to light. It may also increase the risk of skin cancer if used for a long time or over large areas of the body.

Salicylic acid: This is a keratolytic agent that softens and removes psoriasis scales. It is available in different forms, such as creams, lotions, gels, or shampoos. It is usually applied once or twice a day or as needed. An example is MG217. Salicylic acid can cause skin irritation, dryness, or peeling. It may also interfere with the absorption or effectiveness of other topical medications.

The best cream for psoriasis depends on your symptoms, preferences, budget, and response to treatment. You may need to try different products or combinations of products to find what works best for you. You should always consult your doctor before starting any new treatment for ps


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